PHOSPHATIDYLCHOLINE IN INTESTINAL MUCUS PROTECTS AGAINST MUCOSAL INVASION OF MICROBIOTA AND CONSEQUENT INFLAMMATION

Phosphatidylcholine in Intestinal Mucus Protects against Mucosal Invasion of Microbiota and Consequent Inflammation

Intestinal mucus serves as the first line barrier within the mucosa to protect against microbiota attack due to its water-repellent properties, which are the result of the high abundance of phosphatidylcholine bound to mucins.A deficiency of mucus phosphatidylcholine predisposes it to Master Cylinders mucosal inflammation by the attack of commensal

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